Instead of following a bottom up type of design, our genome follows the top down model. A recent press release released by the University of Geneva likens it to a complex orchestra that, naturally, needs a conductor.
According to Professor Bart Deplancke of the École Polytechnique Fédérale de Lausanne:
“Genetic variation at a single genomic position impacted multiple, separated gene regulatory elements at the same time. This extensive coordination was quite surprising, much like a music conductor (i.e. genetic variant) directing all the performers (i.e. transcription factors, chromatin modifications) of a musical ensemble to change the volume (i.e. gene expression) of the music.”
It would not be very logical to attribute this to the blind Darwinian watchmaker. The conductor would need to see what he (or she) is doing.